- Safely removes "dirty" estrogens from reabsorption
- Reduces symptoms of Estrogen Dominance
- Capsule - 60 servings (2-month supply)
Estrogen needs to be cleared from the body in three steps.
Step 1: DIM frees oxidized estrogens in Phase I and the estrogens are passed on to Phase II liver detoxification.
Step 2: Toxins (including "dirty" estrogens) get passed on to the sulfation pathway where they are neutralized. Sulforaphane (Brocco Power) plays a role here.
Step 3: Toxins (including "dirty" estrogens) get passed on to the glucuronidation pathway where they are bound up by glucaric acid (Calcium D-Glucarate) and then fully eliminated from the body.
To graphically explain where DIM, Sulforaphane, and Calcium d-Glucarate play a role in your body, think of a clogged toilet that consists of a toilet bowl and a drain.
With DIM, you have just unclogged your toilet bowl but not the drain. DIM can open the toilet bowl but it's the sulforaphane (and Calcium d-Glucarate) that opens the drain.
2 capsules per day, before or after meals. Take away from Rx medications.
Calcium as Calcium D-Glucarate
Other Ingredients: Hydroxypropyl Methylcellulose Capsule, Vegetable Stearate
Heerdt AS, et al. Calcium glucarate as a chemopreventive agent in breast cancer. Isr J Med Sci 1995;31:101-5.
Abou-issa H, et al. Relative efficacy of glucarate on the initiation and promotion phases of rat mammary carcinogenesis. Anticancer Res 1995;15:805-10.
Walaszek Z, et al. Metabolism, uptake, and excretion of a d-glucaric acid salt and its potential use in cancer prevention. Cancer Detect Prevent 1997;21:178-90.
Yoshimi N, et al. Inhibition of azoxymethane-induced rat colon carcinogenesis by potassium hydrogen D-glucarate. Int J Oncol 2000;16:43-8.
Singh J, Gupta KP. Calcium glucarate prevents tumor formation in mouse skin. Biomed Environ Sci 2003 Mar;16(1):9-16.
Wargovich MJ, Jimenez A, McKee K, et al. Efficacy of potential chemopreventive agents on rat colon aberrant crypt formation and progression. Carcinogenesis. Jun 2000;21(6):1149-1155.
Hanausek M, Walaszek Z, Szemraj J, et al. Modulation of biomarkers during chemoprevention of mouse lung tumorigenesis by D-glucarate. Chest. May 2004;125(5 Suppl):149s.
Lajolo C, Sgambato A, Maiorano E, et al. Calcium glucarate inhibits DMBA-induced oral carcinogenesis in the hamster: histomorphometric evaluation. Anticancer Res. Mar 2010;30(3):843-849."
DO YOU SHIP TO CANADA, THE UK, AUSTRALIA OR OTHER COUNTRIES?
Unfortunately, at this point we only ship to the United States. This is due to the ever-evolving international laws surrounding supplements.
There are forwarding companies like MyUS.com, that will forward orders to you in your country for a fee.
In this case, it is the customer's responsibility to find out in advance if the supplement in question is legal in their country. For example, Progesterone and DHEA are not legal to ship into Canada (Canada classifies bio-identical hormones as drugs so they can only be prescribed by a doctor or naturopath).
We have had customers successfully ship their supplements abroad using MyUS.com, however we have only limited experience with this service.
WHY DOES SHIPPING COST $11.45?
For small businesses like ours, the shipping fee covers the very real costs of getting your order to you: shipping, handling, packaging, warehousing, insurances, and fairly compensating all the people involved along the way. We do our best to keep this shipping cost as low as possible, and offer FREE shipping for orders $97 and above.
WHY DOES MY SUBSCRIPTION ORDER INCLUDE $11.45 SHIPPING?
If you set up a subscription order and notice that you are being charged shipping, it could be due to one of these reasons:
1. Your order value is under $97
2. Your initial order qualifies for free shipping, but the order frequency on your subscriptions is different ( 1 product is set to ship every month, the other is set to ship every 2 months).
*The system automatically splits this kind of order into 2 separate shipments.
In this case it is more economical to set up one subscription every 2 months, and to increase your quantity to 2 units of the supplement that you consume monthly.
For example: 2 Vitamin B6 + 1 Essential Omegas every 2 months = free shipping.
Please email us at firstname.lastname@example.org if you would like some help managing your subscriptions.
How we make things to be delivered directly to you
All our products are rooted in science. No BS, just clean and honest ingredients that work.
No greenwashing means that we don't use misleading marketing to make our products seem more green or eco-friendly. Our products really are as natural as it gets.
We work hard to bring you products that are safe and effective. The top offenders we never invite to the party: GMOs, hormone disruptors, gluten, soy, and dairy.
Our manufacturing facilities are GMP compliant, which means every product is carefully tested. Our products are proudly made in the US and Canada.
Many of our products use botanicals inspired by ancient herbal traditions from around the world.
Our ingredients work synergistically, amplifying each other. We transform them into meaningful products that make a difference for your body and spirit.