Estrogen Reset Kit
- Supports complete estrogen metabolism
- Can help with symptoms of Estrogen Dominance
- Capsules, 60-day supply
- FREE SHIPPING - US Only
*symptoms may be due to low progesterone levels
Estrogen needs to be cleared from the body in three steps.
Step 1: DIM frees oxidized estrogens in Phase I and the estrogens are passed on to Phase II liver detoxification.
Step 2: Toxins (including "dirty" estrogens) get passed on to the sulfation pathway where they are neutralized. Sulforaphane (Brocco Power) plays a role here.
Step 3: Toxins (including "dirty" estrogens) get passed on to the glucuronidation pathway where they are bound up by glucaric acid (Calcium D-Glucarate) and then fully eliminated from the body.
DIM has become the “estrogen buster” of the supplement world. While it can be an effective supplement for some, it doesn’t work as well alone. In fact, many women say they felt worse after taking it. This is most likely due to the fact that DIM upregulates Phase I liver detoxification, opening the floodgates of this phase but leaving with remaining parts of the liver unsupported and overwhelmed by this flooding.
To fully detox excess estrogens, the body also needs a well-supported Phase II liver detoxification. Only when both Phase I and Phase II pathways are nutritionally supported, do you feel at your best and symptoms of Estrogen Dominance get reduced.
To fully understand the 3-Step Complete Estrogen Detoxification process, let’s use a clogged toilet analogy.
DIM will open up the first part of the detoxification process (being the toilet bowl) while Brocco Power (sulforaphane) and Calcium D-glucarate will open up the remaining detoxification (being the drain).
Overcoming Estrogen Dominance offers practical protocols, recipes and meal plans to help transition to an anti-inflammatory diet, while supporting digestive health and gentle liver detoxification, using food and herbs.
Written by Magdalena Wszelaki, who is a functional nutritionist and certified herbalist.
If you have taken DIM, Brocco Power (sulforaphane), and Calcium D-Glucarate before, you can take all three supplements at once and they are best taken with a meal. You can take all three supplements with the same meal each day (breakfast, lunch, or dinner), or space them out throughout the day with meals. Whatever routine works best for you.
If you are new to the Estrogen Reset Kit and/or sensitive to supplements, we recommend introducing these three supplements one at a time.
Continue to take all three supplements daily with meals. If any of the supplements give you adverse reactions, please discontinue it.
DIM upregulates Phase I liver detoxification which is important in estrogen clearing (and to mitigate symptoms of Estrogen Dominance) but it’s not the only liver detoxification pathway used by the body to clear “dirty” estrogens and mitigate symptoms. We also need support for Phase II liver detoxification (by taking Brocco Power and Calcium D-Glucarate) to fully address Estrogen Dominance.
Because some women do feel worse when they start taking DIM, we recommend introducing the supplements in the Estrogen Reset Kit as follows:
Rajoria S, Suriano R, Parmar PS, et al. 3,3'-diindolylmethane modulates estrogen metabolism in patients with thyroid proliferative disease: a pilot study.Thyroid. 2011;21(3):299-304. doi:10.1089/thy.2010.0245
Wang SQ, Cheng LS, Liu Y, Wang JY, Jiang W. Indole-3-Carbinol (I3C) and its Major Derivatives: Their Pharmacokinetics and Important Roles in Hepatic Protection. Curr Drug Metab. 2016;17(4):401-9. doi: 10.2174/1389200217666151210125105. PMID: 26651978.
Lord RS, Bongiovanni B, Bralley JA. Estrogen metabolism and the diet-cancer connection: rationale for assessing the ratio of urinary hydroxylated estrogen metabolites. Altern Med Rev. 2002 Apr;7(2):112-29. PMID: 11991791. Morales-Prieto, D. M., Herrmann, J., Osterwald, H., Kochhar, P. S., Schleussner, E., Markert, U. R., & Oettel, M. (2018). Comparison of dienogest effects upon 3,3'-diindolylmethane supplementation in models of endometriosis and clinical cases. Reproductive biology, 18(3), 252–258. https://doi.org/10.1016/j.repbio.2018.07.002
Thomson, C. A., Ho, E., & Strom, M. B. (2016). Chemopreventive properties of 3,3'-diindolylmethane in breast cancer: evidence from experimental and human studies.
Nutrition reviews,74 (7), 432–443. https://doi.org/10.1093/nutrit/nuw010 Yoshida K, Ushida Y, Ishijima T, et al. Broccoli sprout extract induces detoxification-related geneexpression and attenuates acute liver injury. World J Gastroenterol. 2015;21(35):10091–10103.doi:10.3748/wjg.v21.i35.10091. Retrieved from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572790/
Castro, N. P. et al. Sulforaphane suppresses the growth of triple-negative breast cancer stem-like cells invitro and in vivo. Cancer Prev. Res. (Phila.)1 2,147–158 (2019). Retrieved from: https://www.ncbi.nlm.nih.gov/pubmed/30679159
Bahadoran, Z., Mirmiran, P., & Azizi, F. (2013). Potential efficacy of broccoli sprouts as a unique supplement for management of type 2 diabetes and its complications. Journal of medicinal food, 16(5), 375–382. https://doi.org/10.1089/jmf.2012.2559
Chartoumpekis, D. V., Ziros, P. G., Chen, J. G., Groopman, J. D., Kensler, T. W., & Sykiotis, G. P. (2019). Broccoli sprout beverage is safe for thyroid hormonal and autoimmune status: Results of a 12-week randomized trial. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 126, 1–6. https://doi.org/10.1016/j.fct.2019.02.004
Kuran, D., Pogorzelska, A., & Wiktorska, K. (2020). Breast Cancer Prevention-Is there a Future for Sulforaphane and Its Analogs?
Nutrients,12 (6), 1559. https://doi.org/10.3390/nu12061559
Calcium-D-glucarate. (2002). Alternative medicine review : a journal of clinical therapeutic, 7(4), 336–339.
Heerdt, A. S., Young, C. W., & Borgen, P. I. (1995). Calcium glucarate as a chemopreventive agent in breast cancer.
Israel journal of medical sciences, 31(2-3), 101–105.
DO YOU SHIP TO CANADA, THE UK, AUSTRALIA OR OTHER COUNTRIES?
Unfortunately, at this point we only ship to the United States. This is due to the ever-evolving international laws surrounding supplements.
There are forwarding companies like MyUS.com, that will forward orders to you in your country for a fee.
In this case, it is the customer's responsibility to find out in advance if the supplement in question is legal in their country. For example, Progesterone and DHEA are not legal to ship into Canada (Canada classifies bio-identical hormones as drugs so they can only be prescribed by a doctor or naturopath).
We have had customers successfully ship their supplements abroad using MyUS.com, however we have only limited experience with this service.
WHY DOES SHIPPING COST $11.45?
For small businesses like ours, the shipping fee covers the very real costs of getting your order to you: shipping, handling, packaging, warehousing, insurances, and fairly compensating all the people involved along the way. We do our best to keep this shipping cost as low as possible, and offer FREE shipping for orders $97 and above.
WHY DOES MY SUBSCRIPTION ORDER INCLUDE $11.45 SHIPPING?
If you set up a subscription order and notice that you are being charged shipping, it could be due to one of these reasons:
1. Your order value is under $97
2. Your initial order qualifies for free shipping, but the order frequency on your subscriptions is different ( 1 product is set to ship every month, the other is set to ship every 2 months).
*The system automatically splits this kind of order into 2 separate shipments.
In this case it is more economical to set up one subscription every 2 months, and to increase your quantity to 2 units of the supplement that you consume monthly.
For example: 2 Vitamin B6 + 1 Essential Omegas every 2 months = free shipping.
Please email us at support@hormonesbalance.com if you would like some help managing your subscriptions.
If you have taken DIM, Brocco Power (sulforaphane), and Calcium D-Glucarate before, you can take all three supplements at once and they are best taken with a meal. You can take all three supplements with the same meal each day (breakfast, lunch, or dinner), or space them out throughout the day with meals. Whatever routine works best for you.
If you are new to the Estrogen Reset Kit and/or sensitive to supplements, we recommend introducing these three supplements one at a time.
Continue to take all three supplements daily with meals. If any of the supplements give you adverse reactions, please discontinue it.
DIM upregulates Phase I liver detoxification which is important in estrogen clearing (and to mitigate symptoms of Estrogen Dominance) but it’s not the only liver detoxification pathway used by the body to clear “dirty” estrogens and mitigate symptoms. We also need support for Phase II liver detoxification (by taking Brocco Power and Calcium D-Glucarate) to fully address Estrogen Dominance.
Because some women do feel worse when they start taking DIM, we recommend introducing the supplements in the Estrogen Reset Kit as follows:
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Many of our products use botanicals inspired by ancient herbal traditions from around the world.
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