Happy Sisters Cream

Original price $59.97 - Original price $119.94
Original price $59.99
$19.99 - $119.94
Current price $19.99
  • Happy Sisters Overstock Sale. Save 66% for a limited time.
  • Supports optimal breast health
  • Daily maintenance and prevention
  • Benefits estrogen balance, lymphatic system, and inflammatory responses
  • 1.7 oz daily topical breast cream
  • Best by 8/2024
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We understand the overwhelming fear of finding a breast lump, skipping a workout due to breast pain, or not being able to put on a bra because our "sisters" hurt so bad.

How Happy Sisters Cream can support breast health

  • May reduce breast pain
  • May reduce fibrocystic breast lumps
  • May reduce inflammatory responses in the breast
  • Supports the lymphatic system

The herbs and oils in this formula can help by:

  • Poke Root Infused Oil - Relieves painful breasts
  • St. John’s Wort Infused Oil - Promotes hormone balance and detoxification
  • Borage Seed Cold-Pressed Oil Featuring GLA - Reduces swelling and tenderness
  • Ginger Infused Oil - Lymph mover
  • Black Seed Cold-Pressed Oil - Relieves breast tenderness
  • Rose Geranium Essential Oil - Improves lymph circulation
  • Bergamot FCF Essential Oil - Calming, balancing, and uplifting

"I’m all pain-free and finally have peace of mind"
This is our #1 selling... “Went for my mammogram... And it said that both breasts were completely clear, so the cyst was gone. And I have to believe that the cream did it."
"Two weeks before my period, I don't even want to wear a bra. But since using this product, my discomfort has gone from a level 10 to a level 3 and that's a huge difference in my world."
"This is a game changer for women who experience breast pain or fibrocystic breasts."
"The cream provided instant relief for my tender breasts."
"I was diagnosed with Fibrocystic Cysts in my left breast; the Happy Sisters Kit is my miracle."
"I'm in perimenopause and there's certain times of the month where it feels impossible to wear a bra. Happy Sisters helped me find relief from breast discomfort."
"After the birth of my first born child, I had a terrible case of mastitis that resulted in a calcified lymph node and just left me with an achy breast. After using this for about a month, the achiness went away."

Featured Ingredients

Poke Root Oil Traditionally used herb for moving the lymph, clearing lumps, swelling, and tissue congestion. strong lymph mover for clearing lumps, swelling, and tissue congestion. The infused oil is a standard topical treatment for painful or swollen breasts.
St. John’s Wort Oil A beautiful herb with a distinct affinity for breast tissue. Topical application helps to relieve premenstrual breast discomfort and bypasses potential herb/drug interactions that might limit its use internally.
Borage Seed Oil A particularly rich source of GLA, a beneficial fatty acid that supports a healthy inflammatory response both directly on affected tissue, as well as systemically. A wonderful herb shown to reduce breast tenderness and swelling.
Ginger Oil A touch of ginger is a traditional favorite in formulas for premenstrual breast discomfort. Topical ginger oil promotes a healthy inflammatory response, clears obstruction, and promotes healthy detoxification processes.
As a hormone nutritionist and herbalist, I’ve struggled with fibrocystic breasts and benign lumps most of my life. — Magdalena, founder of Wellena and creator of Happy Sisters

How to use the cream

Start with clean skin and follow the lymphatic massage instructions below. 

1. Scoop out 1/4 to 1/2 teaspoon of the cream and lightly spread over your breast tissue. 

2. Massage with your opposite side hand in the direction of lymphatic flow - away from the nipple toward 12:00, then back to the nipple and toward 2:00, then repeat to 4:00, 6:00, 8:00, and 10:00.

3. Go slow, about three to five seconds per sweep, and gentle but deep.

4. Repeat as needed.

5. Visualize the breast as being made of sponge containing thick honey. Slow, deep sweeps make the honey flow out.

6. Finish by visualizing your breasts being nourished, cleansed, and healed.

How to perform a lymphatic massage
How to use the cream
1/4 - 1/2 tsp per day

Recommended use: Massage into breast tissue at least once a day, as needed.

Our Ingredients

Aloe Barbadensis Leaf Juice, Olive Oil, Borage Seed Oil, Safflower Seed Oil, Black Cumin Seed Oil, Castor Seed Oil, Cetearyl Olivate (and) Sorbitan Olivate, Glycerin, Shea Butter, Acacia Senegal Gum (and) Xanthan Gum, Poke Root Extract, St. John’s Wort Extract, Ginger Root Extract, Alkanet Root Extract, Rosemary CO2 Extract, Triethyl Citrate, Glyceryl Caprylate, Benzoic Acid, Geranium Flower Oil, Ylang Ylang Flower Oil, Bergamot Peel Oil  

Happy Sisters Cream works best with:

Happy Sisters Supplement A powerful blend of herbs, minerals, and oils addresses the underlying causes of breast issues; estrogen dominance, inflammation, and lymphatic stagnation. $69.99
ProgestPure Cream Highly bioavailable cream provides 25 mg of bioidentical progesterone per serving $69.99
B Maximus Supports liver detoxification, estrogen balance, and energy $32.99

Quality Check

A quality supplement should:
  • contain herbs that have been 3rd party tested for efficacy
  • contain no fillers and additives
  • be made in a GMP facility


COMT methylation protective against undesirable estrogen metabolites https://pubmed.ncbi.nlm.nih.gov/11606384/

Magnesium, PMS, mastalgia https://pubmed.ncbi.nlm.nih.gov/6684167/

Magnesium: physiology and pharmacology https://www.bjanaesthesia.org/article/S0007-0912(17)38397-6/pdf

Magnesium glycinate and myometrial relaxation https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071389/pdf/nutrients-12-00573.pdf

Article on estrogen metabolism, COMT, and magnesium by a physician / biochemist https://www.drlaurendeville.com/articles/estrogen-detoxification/

Calcium D-glucarate monograph - https://altmedrev.com/wp-content/uploads/2019/02/v7-4-336.pdf

Calcium D-glucarate as a beta-glucuronidase inhibitor https://pubmed.ncbi.nlm.nih.gov/18772850/

Article on Calcium D-glucarate and estrogen metabolism, NMD journal https://ndnr.com/endocrinology/estrogen-dominance-in-women/

Article on Calcium D-glucarate from a functional medicine physician / biochemist https://drbrighten.com/benefits-of-calcium-d-glucarate/

Composition and physiological activities of Borage seed oil - https://pubmed.ncbi.nlm.nih.gov/25312125/

GLA and cyclic mastalgia https://pubmed.ncbi.nlm.nih.gov/18296341/

GLA, eicosanoids, and inflammation https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975646/pdf/nihms781789.pdf

Borage oil and inflammatory gene expression https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708836/pdf/zbc15400.pdf

GLA and PMS-associated inflammation / dysmenorrhea https://pubmed.ncbi.nlm.nih.gov/18296341/

Black seed oil for cyclic mastalgia https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820470/pdf/2093-6966-v22-n03-131.pdf

Black seed oil as an anti-inflammatory agent https://pubmed.ncbi.nlm.nih.gov/33559935/

Nigella sativa: monograph https://www.phytojournal.com/archives/2015/vol4issue4/PartB/4-3-79.pdf

Black seed oil for breast health: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460502/pdf/medicines-07-00047.pdf and https://pubmed.ncbi.nlm.nih.gov/26964971/ and https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921197/pdf/main.pdf

See the extensive clinical monograph on Phytolacca in Principles and Practice of Phytotherapy, 2nd. Ed., Simon Mills & Kerry Bone. London, UK: Churchill Livingstone/Elsevier; 2013. Pp. 795-798.

Phytolacca in King’s American Dispensatory, the standard Eclectic medical publication of 1898 https://www.henriettes-herb.com/eclectic/kings/phytolacca.html

Ruth Trickey (with practitioners from the Melbourne Holistic Health Group), respected midwife and herbalist, mentions the use of Poke for mastalgia in her classic Women, Hormones & the Menstrual Cycle, 3rd Ed., Trickey Enterprises (Victoria) Pty, Limited; 2011.

Bioactive triterpene saponins from Phytolacca americana https://pubmed.ncbi.nlm.nih.gov/33002830/

Dr. Aviva Romm mentions topical Phytolacca for benign breast disease in Botanical Medicine for Women’s Health (p. 595), Churchill Livingstone; 2nd Ed.; 2017.

Effective medicinal plants for cyclic mastalgia, a review https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820470/

Topical application of St. John’s Wort https://pubmed.ncbi.nlm.nih.gov/24214835/

Anti-inflammatory mechanisms of Hypericum oil https://pubmed.ncbi.nlm.nih.gov/24993886/

Cell-growth regulating effects of the oil-soluble constituents https://pubmed.ncbi.nlm.nih.gov/33379141/

See the extensive clinical monograph on Hypericum in Principles and Practice of Phytotherapy, 2nd. Ed., Simon Mills & Kerry Bone. London, UK: Churchill Livingstone/Elsevier; 2013. Pp. 826-860.

Parsay S, Olfati F, Nahidi S. Therapeutic effects of vitamin E on cyclic mastalgia. Breast Journal. 2009;15:510–4. Retrieved from: https://www.ncbi.nlm.nih.gov/pubmed/19614907

American Herbal Pharmacopoeia (AHP) monograph on Trifolium http://pharmaguri.co.il/_Uploads/dbsAttachedFiles/AHPTrifoliumMonograph.pdf

Review – pharmacology of the main isoflavonoid in Trifolium, Biochanin A https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639423/pdf/fphar-10-00793.pdf

Trifolium’s potential as a complementary therapy in breast cancer (apoptotic, antioxidant, anti-inflammatory) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455927/

Pharmacological and therapeutic properties of Red Clover 2021 https://pubmed.ncbi.nlm.nih.gov/34392659/

Isoflavones (Trifolium constituent) and mastalgia, clinical trial https://pubmed.ncbi.nlm.nih.gov/14965665/

Clinical actions of Red Clover https://restorativemedicine.org/library/monographs/red-clover/

Anti-inflammatory activity of Andrographis and andrographolide https://pubmed.ncbi.nlm.nih.gov/25888070/

Anti-inflammatory diterpenoid lactones in Andrographis https://pubmed.ncbi.nlm.nih.gov/31357563/

Andrographis review: ethnobotany, phytochemistry, pharmacology https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408759/pdf/TSWJ2014-274905.pdf

See the extensive clinical monograph on Andrographis in Principles and Practice of Phytotherapy, 2nd. Ed., Simon Mills & Kerry Bone. London, UK: Churchill Livingstone/Elsevier; 2013. Pp. 360-372.

See Discover Andrographis by Alexander Panossian, Ph.D. Detailed monograph/book. https://www.academia.edu/40480219/DISCOVER_ANDROGRAPHIS


Unfortunately, at this point we only ship to the United States. This is due to the ever-evolving international laws surrounding supplements.

There are forwarding companies like MyUS.com, that will forward orders to you in your country for a fee.

In this case, it is the customer's responsibility to find out in advance if the supplement in question is legal in their country. For example, Progesterone and DHEA are not legal to ship into Canada (Canada classifies bio-identical hormones as drugs so they can only be prescribed by a doctor or naturopath).

We have had customers successfully ship their supplements abroad using MyUS.com, however we have only limited experience with this service.


For small businesses like ours, the shipping fee covers the very real costs of getting your order to you: shipping, handling, packaging, warehousing, insurances, and fairly compensating all the people involved along the way. We do our best to keep this shipping cost as low as possible, and offer FREE shipping for orders $97 and above.


If you set up a subscription order and notice that you are being charged shipping, it could be due to one of these reasons:

1. Your order value is under $97

2. Your initial order qualifies for free shipping, but the order frequency on your subscriptions is different ( 1 product is set to ship every month, the other is set to ship every 2 months).

*The system automatically splits this kind of order into 2 separate shipments.

In this case it is more economical to set up one subscription every 2 months, and to increase your quantity to 2 units of the supplement that you consume monthly.

For example: 2 Vitamin B6 + 1 Essential Omegas every 2 months = free shipping.

Please email us at support@hormonesbalance.com if you would like some help managing your subscriptions.

How we make things to be delivered directly to you

Science. Research. Facts.

All our products are rooted in science. No BS, just clean and honest ingredients that work.

We don’t greenwash. Ever.

No greenwashing means that we don't use misleading marketing to make our products seem more green or eco-friendly. Our products really are as natural as it gets.

If it’s not squeaky clean, it’s out.

We work hard to bring you products that are safe and effective. The top offenders we never invite to the party: GMOs, hormone disruptors, gluten, soy, and dairy.

Rigorously tested

Our manufacturing facilities are GMP compliant, which means every product is carefully tested. Our products are proudly made in the US and Canada.

Time-honored traditions

Many of our products use botanicals inspired by ancient herbal traditions from around the world.

1+1 = 5

Our ingredients work synergistically, amplifying each other. We transform them into meaningful products that make a difference for your body and spirit.