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270 reviews

 This product is currently available as subscription-only*. To make a regular purchase, please email  support@hormonesbalance.com for assistance. 

ProgestPure is a highly bioavailable and natural topical progesterone serum providing 20 mg of bioidentical progesterone in each 1 ml serving. It is made from yams - it is then modified in the lab for the progesterone molecule to resemble a human progesterone molecule.

  • Natural bioidentical progesterone can normalize hormone imbalances with fewer side-effects than synthetic progestins.
  • Reproductive age- Supporting progesterone levels in the body may increase the likelihood of a healthy cycle.
  • Menopausal / post-menopausal age- Supporting progesterone levels in the body may help make this significant life change more pleasant.

Made with non-GMO ingredients. This product is free of parabens, mineral oil, and petroleum. 

 Suggested Use*:

  • Apply 1-2 times per day to smooth skin areas, such as wrists, inner arms or thighs, throat, neck, abdomen or chest, or
  • as directed by a health care practitioner.
  • For optimal use, rotate the areas of application.
  • Menstruating women: Apply 1 ml of ProgestPure (1 full dropper) once or twice per day on days 14 through 27 of the menstrual cycle, or as directed by a health care professional.
  • Menopausal and post-menopausal women: Apply 1 ml of ProgestPure (1 full dropper) once or twice per day for 25 consecutive days, followed by a 5-day break, or as directed by a health care professional.

Note: Consult your functional doctor or naturopath for dosage instructions based on your specific hormone levels.

*Results are individual and depend on your health status.

For a full description:



"Proposition 65, the Safe Drinking Water and Toxic Enforcement Act of 1986" was originally intended to protect drinking water sources from chemicals known to cause cancer, birth defects or other reproductive harm, and to inform citizens about exposures to such chemicals. Each year the Governor posts a list of chemicals "known to the state to cause cancer or reproductive toxicity.

Progesterone is on the list.

Progesterone is a hormone that actually prevents cancer, it also helps with your thyroid, sleep, cycle and moods. It It is necessary for a healthy pregnancy and for bone health. Progesterone also helps reduce the typical symptoms of menopause (mood changes, hot flashes, insomnia, weight gain, thyroid disfunction, loss of libido, etc...)

There are four major flaws in the study that caused progesterone to be added to the Prop 65 warning list:  

1- The vast majority of the studies implicating progesterone were done on SYNTHETIC progesterone (progestins and other progesterone-like compounds called progestagens). These studies were NOT based on BIO-IDENTICAL progesterone (as used in our ProgestPure).  

Progestins and progestagens are similar in molecular structure to progesterone, but when they bind to progesterone receptors, their effects are amplified and more likely to cause abnormal responses- just like the ones in birth control pills.

2- The majority of the studies were done in combination with synthetic estrogens. Again,  ProgestPure does not use ANY synthetic hormones.

3-  The few studies done on bio-identical progesterone were done with excessive and unreal doses (from 10 times to 10000 times the standard recommended dose).

4- No studies were done using transdermal creams. Only oral, injected and suppository forms were used. This is important to note because hormones absorbed through the skin are metabolized differently than hormones that are administered via other means. 

Click HERE to view the study that wrongly implicated bio-identical progesterone.

We were very surprised to hear that our product would bear such a warning, despite it being one of the purest bio-identical progesterone oils available.

We created this product despite the law requiring this warning. We did it because we know how many women will experience relief of their painful symptoms. And, because we know that estrogen dominance is one of the leading causes of breast, uterine, ovarian and thyroid cancers.

Please note that our team personally use ProgestPure. 


We were forced into making the product "subscription-only" on the storefront because we were unfairly flagged by one of our payment processors for selling a "hormone". Apparently a customer attempted to ship the product internationally through a forwarding service and it was refused at customs, and the processor flagged the product.

In the US bio-identical progesterone is perfectly legal, but it is regulated as a drug in many other countries. The payment processor gave us a choice to stop selling the product altogether or make it so that this processor cannot be used as an option for payment when someone has the product in their cart.

The only way that we can control the payment processor options currently is with subscription orders. We are in the process of disputing the ruling with the processor, but these things take time. In the meantime, this is the best workaround that we can offer. Customer Support can set up a regular order with you anytime.


Customer Reviews
4.8 Based on 270 Reviews
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Cheyenne H.
United States United States

I will be starting my 2nd month with this product. I use 1 dropper full, 1x per day from say 14 to approx day 27. After many years of knowing something wasn't right but not receiving any help from Dr's, I took matters in to my own hands. I sadly experienced 5 pregnancy losses and it was only after I started natural progesterone could my husband and I celebrate the birth of our son. However, it wasn't only my fertility issues, I also suffer from bloating and weight gain around my belly and thighs. I can honestly say ProgestPure is really starting to make a difference. My face and my entire body is less bloated. I have major decreased PMS symptoms (husband is very releaved ;)) I live in The Netherlands and use myus.com to have the product sent to me. I've used their shipping service twice now and am very satisfied with it.

Wellena / Hormones Balance

Wow, thank you for such an amazing review!! We are thrilled to be part of your healing journey. >3

Kimberly W.
United States United States

Great product! I like that it is an oil and not a lotion. Absorbed very easily without leaving my skin greasy.

Beth W.
United States United States
Seems to help my mood

I am just finishing up the first bottle and feel a definite difference. I forgot for two days while traveling to use the ProgestPure and could tell I had quite a change in my mood. I do feel that the ProgestPure is making a difference for me and have ordered a second bottle.

Emma S.
United States United States
Hair growth

I’ve had successful use for hair growth. I’ve been applying the oil on my scalp and over a month or so, I’ve noticed hair growing again in areas that I had thinning.

Alexandra B.
United States United States
Just get it!

Love this. I have struggled to find the right progesterone for me. I am only 23 but have struggled with my progesterone levels for a long time. This has been the first product that has worked well without making me feel sick with use.

Wellena / Hormones Balance

Happy to hear this product is working well for you. =)